High protein diets modulate renal lipid metabolism in Zucker fa/fa rats

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High-protein diets and renal status in rats.

INTRODUCTION High-protein (HP) diets might affect renal status. We aimed to examine the effects of a HP diet on plasma, urinary and morphological renal parameters in rats. MATERIAL AND METHODS Twenty Wistar rats were randomly distributed in 2 experimental groups with HP or normal-protein (NP) diets over 12 weeks. RESULTS AND DISCUSSION Final body weight was a 10%lower in the HP group (p < 0...

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Glycemic index differences of high-fat diets modulate primarily lipid metabolism in murine adipose tissue.

A low vs. high glycemic index of a high-fat (HF) diet (LGI and HGI, respectively) significantly retarded adverse health effects in adult male C57BL/6J mice, as shown recently (Van Schothorst EM, Bunschoten A, Schrauwen P, Mensink RP, Keijer J. FASEB J 23: 1092-1101, 2009). The LGI diet enhanced whole body insulin sensitivity and repressed HF diet-induced body and white adipose tissue (WAT) weig...

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Leucine and Protein Metabolism in Obese Zucker Rats

Branched-chain amino acids (BCAAs) are circulating nutrient signals for protein accretion, however, they increase in obesity and elevations appear to be prognostic of diabetes. To understand the mechanisms whereby obesity affects BCAAs and protein metabolism, we employed metabolomics and measured rates of [1-(14)C]-leucine metabolism, tissue-specific protein synthesis and branched-chain keto-ac...

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The Effects of Fermented Soy and Soy Diets on Lipid Composition of Zucker (fa/fa) Rats

...........................................................................2 Introduction .......................................................................3 Materials and Methods..........................................................7 Results...........................................................................13 Discussion.............................................................

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The effect of lowered environmental temperature on lipid metabolism in rats fed on normal and high-fat, high-cholesterol diets.

I. Prolonged intermittent exposure to reduced environmental temperature (+ 2") produced in rats given a nutritionally well-balanced diet a decrease in the concentration of esterified fatty acids in the blood serum, liver and epididymal fat tissue. In the last there was a significant increase in the unesterified: esterified fatty acid ratio. The hepatic synthesis of fatty acids from [1-14C]aceta...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2010

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.24.1_supplement.733.5